Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies
نویسندگان
چکیده
منابع مشابه
Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies
Recently identified broadly neutralizing antibodies (bNAbs) that potently neutralize most HIV-1 strains are key to potential antibody-based therapeutic approaches to combat HIV/AIDS in the absence of an effective vaccine. Increasing bNAb potencies and resistance to common routes of HIV-1 escape through mutation would facilitate their use as therapeutics. We previously used structure-based desig...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2013
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.20130221